Ebola Hemorrhagic Fever and Pregnancy

Kibadi Mupapa, Woliere Mukundu, Mpia Ado Bwaka, Mungala Kipasa, Ann De Roo, Kivudi Kuvula, Kapay Kibadi, Matondo Massamba, Djuma Ndaberey, Robert Colebunders, and J. J. Muyembe-Tamfum


Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of
the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women
(66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3
received a blood transfusion from an apparently healthy person. One woman was prematurely
delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy.
All women presented with severe bleeding. Only 1 survived; she had a curettage because of an
incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with
Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality
observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

ARTICLE - Ebola Hemorragic Fever and Pregnancy - Fievre hemorragique à Virus Ebola et grossesse -J Infect Dis 1999 - Prof Dr Kibadi K et al

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